A new medication that treats binge eating disorders and obesity may be on the way. According to a recent study published in Neuropsychopharmacology, PACAP (pituitary adenylate cyclase-activating peptide) can reduce one’s urge to eat when administered to the central amygdala.
PACAP is a hormone and peptide combo created by neurons. Before being presented food, participants were injected with PACAP in their amygdala. Come meal time they ate fewer calories, either by consuming less when having normal size meals or consuming smaller meals all together. They also ate more slowly.
Researchers have known PACAP’s suppressant qualities when applied to the hypothalamus but this study is the first to show its effect in other regions of the brain. It’s working as an appetite suppressant is dependent on brain-derived neurotrophic factor (BDNF) but the results of the study could be promising for those devoted to assisting those who need significant help losing weight for health purposes.